Team Leader in Medicinal Chemistry, Cancer Research UK Cancer Therapeutics Unit

Ref: 3767

The Institute of Cancer Research

London / Sutton

Role Managed by:

Dr Urvashi Ramphul

Senior Research Associate

t: +44 (0) 20 7340 6280

f: +44 (0) 20 7340 6201


Primary Practice Group: Higher Education and Research

Salary & Benefits: Competitive

Closing Date: 28/06/2019

Formal Interview Date: September 2019

This vacancy has now expired, and is not accepting any new applications.

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The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. The ICR are world leaders in identifying cancer genes, discovering cancer drugs and developing precision radiotherapy. Together with its hospital partner The Royal Marsden NHS Foundation Trust, they are rated in the top four centres for cancer research and treatment worldwide. The ICR works closely with funding organisations including Cancer Research UK, Breast Cancer Now and the Wellcome Trust to deliver its programme of research.

The Cancer Research UK Cancer Therapeutics Unit (CTU) within Division of Cancer Therapeutics is ranked among the world’s best academic cancer drug discovery and development groups. Led by Professor Raj Chopra, CTU is a multidisciplinary 'bench to bedside' centre, comprising around 170 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. Its 12 research teams cover every aspect of new drug discovery and development, from cell and molecular biology through to chemical synthesis of new agents and their evaluation in clinical trials.

CRUK CTU now seeks to appoint a Team Leader in Medicinal Chemistry who will lead an independent chemistry research team that will contribute to the overall strategy and goals of the CTU. Reporting to the Unit Director Professor Raj Chopra and the Head of Chemistry Professor Ian Collins, the successful appointee will lead the application of medicinal and synthetic chemistry approaches to progress innovative small molecule anticancer compounds to proof-of-concept clinical trials. Commitment to translational and drug discovery research is critical to this position.

The successful candidate will be an established medicinal chemist with experience in drug discovery, and demonstrable ability to develop a research programme aligned with the overall research strategy of CTU. With the opportunity to appoint a number of core-funded scientists to their team, the post holder will have a reputation for high quality research and intellectual leadership, and the ability to personally lead and mentor a laboratory research team. Experience of drug discovery and translational research is essential, and experience of working within a pharmaceutical or biotechnology company is highly desirable. Enthusiasm for working in a focussed and collaborative interdisciplinary environment is essential. The successful candidate will have the drive and ability to publish high quality research in leading medicinal chemistry and/or chemical biology journals, and to pursue funding opportunities for new areas of research.


For informal inquiries please contact Professor Ian Collins at the ICR at     or +44 (0)20 8722 4317, or Dr Urvashi Ramphul at          or +44 20 7340 6280. Applications should consist of a letter of motivation and a complete curriculum vitae including a publication and patent application list. The closing date for applications is Friday 28th June. Applications will be considered by the selection committee in early July and shortlisted candidates will subsequently be invited for campus visits and first stage interviews with representatives from the Division of Cancer Therapeutics. Final interviews are expected to take place in September 2019.

This vacancy has now expired, and is not accepting any new applications.

Please search for live opportunities or use the Register Interest facility to sign up for job alerts and/or leave your CV speculatively.