Team Leader in Drug Discovery Biology

Ref: 3766

The Institute of Cancer Research


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Role Managed by:

Dr Urvashi Ramphul

Senior Research Associate

t: +44 (0) 20 7340 6280

f: +44 (0) 20 7340 6201


Primary Practice Group: Higher Education and Research

Salary & Benefits: Competitive

Closing Date: 12/11/2018

Formal Interview Date: Early 2019

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. The ICR are world leaders in identifying cancer genes, discovering cancer drugs and developing precision radiotherapy. Together with its hospital partner The Royal Marsden NHS Foundation Trust, they are rated in the top four centres for cancer research and treatment worldwide. The ICR works closely with funding organisations including Cancer Research UK, Breast Cancer Now and the Wellcome Trust to deliver its programme of research. Research at the ICR is structured into eight research divisions and more than 70 research teams.

The Cancer Research UK Cancer Therapeutics Unit (CTU) within the Division of Cancer Therapeutics is the largest, and ranked among the best, academic cancer drug discovery and development groups in the world. Led by Professor Raj Chopra, CTU is a multidisciplinary 'bench to bedside' centre, comprising around 170 staff dedicated to the discovery and development of novel therapeutics for the treatment of cancer. Its 12 research teams cover every aspect of new drug discovery and development, from cell and molecular biology through to chemical synthesis of new agents and their evaluation in clinical trials.

CRUK CTU now seeks to appoint a new Team Leader in Drug Discovery Biology who will lead an independent cancer biology research group that will contribute to the overall strategy and goals of the CTU. Reporting to the Unit Director, Professor Raj Chopra, and the Head of Biology, Dr Olivia Rossanese, the successful appointee will have a particular focus on progression of innovative small molecule anticancer compounds to proof-of-concept clinical trials. Commitment to translational and drug discovery research is fundamental to this position.

The successful candidate will be a Team Leader pursuing her/his own oncology research programme aligned with the overall research strategy of CTU. With the opportunity to appoint a number of core-funded scientists to their team, s/he will have the proven leadership skills and international research credibility to manage a multidisciplinary project team. Excellent knowledge of cancer and its biology, and of translational aspects of cancer biology is essential. S/he will have an international reputation in oncology biology and/or pharmacology in the academic or biotech/pharma sectors with research ideally aligned with one or more of CTU’s core research themes: Non-Oncogene Addiction; Genomic Instability; Tumour-Host Interaction; Cellular State and Plasticity.

Applications should consist of a letter of motivation and a complete curriculum vitae including a publication and research funding list. The closing date for applications is Monday 12th November. Applications will be considered by the recruitment committee in late November and shortlisted candidates will subsequently be invited for campus visits and first stage interviews with representatives from the Division of Cancer Therapeutics in early December. Final interviews will take place in early 2019.